Robert Mistrík - Prednášky

Prednášky na medzinárodných kongresoch, konferenciách a sympóziách

Keynote, Plenary and Invited prednášky

Keynote - EUROTOX 2017, 53rd Congress of the European Societies of Toxicology, Bratislava, Slovakia
September 10-13, 2017
The growing analytical fallacy: The majority of small molecules on earth remains unidentified, while hundreds of molecules have been reported in space

Keynote - 37th British Mass Spectrometry Society annual meeting, Eastbourne, UK
September 13-15, 2016
mzCloud: A comprehensively annotated LC/MSn database for the identification of unknowns

Invited Plenary - 33rd meeting of the Swiss Group for Mass Spectrometry, Beatenberg, Switzerland
October 29-30, 2015
The great paradox of the 21st century: We are unable to identify 70-90% of small molecules in biological samples and rivers on Earth, while humans have endeavored to analyze the soil on Mars, the atmosphere on Jupiter and the sea on Titan.

Keynote - International Mass Spectrometry Conference, 2014, Geneva, Switzerland
August 24-29, 2014
Beyond the elemental composition: Computer-assisted identification methods in a high resolution era

Keynote - 29th Montreux Symposium on LC/MS, Montreux, Switzerland
November 7, 2012
Identification of Unknowns using Mass Spectral Library Cloud

Invited Plenary– TOXCON 2010, Stará Lesná, Slovakia
September 9, 2010
Xenobiotic Metabolite Detection using High Resolution Tandem Mass Spectrometry

Invited - Metabolomics Society 4th Annual Conference, Boston, MA, USA
September 3-6, 2008
Integrated Approach for Structural Analysis of Endogenous
Robert Mistrik, HighChem, Slovakia

Key Note Lecture - MassSpec-Forum, Vienna, Austria
February 20 - 21, 2007
A „Cool“ Outlook on „Uncool“ Fragmentation Processes
Robert Mistrik, HighChem, Slovakia

Vybrané prednášky

46th EuroCongress on Drug Synthesis and Analysis, Bratislava, Slovakia
September 5-8, 2017
The next step towards deciphering nature’s molecules: Mapping human and other organisms' metabolomes

VI. Conference on biological psychiatry
June 6, 2017
A Journey into the Molecular Depth of the Brain

65th ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, USA
June 4-8, 2017
Paradigm Change in de novo Identification of Small Molecules: Giant Spectral Trees

37th British Mass Spectrometry Society annual meeting, Eastbourne, UK
September 13-15, 2016
mzCloud: A comprehensively annotated LC/MSn database for the identification of unknowns

12th Annual Conference of the Metabolomics Society, Dublin, Ireland
June 27-30, 2016
mzCloud: An online substructural database of spectral trees for the identification of metabolites

SULSA Scottish Metabolomics Network Inaugural Meeting, University of Edinburgh, UK
November 30-December 1, 2015
Applying mzCloud in known and unknown metabolite ID applied to metabolomics

Extractables & Leachables Europe 2015, London, UK
November 10-12, 2015
Development and Utilization of Cloud Based Libraries for Unknown Contaminant Identification

33rd meeting of the Swiss Group for Mass Spectrometry, Beatenberg, Switzerland
October 29-30, 2015
The great paradox of the 21st century: We are unable to identify 70-90% of small molecules in biological samples and rivers on Earth, while humans have endeavored to analyze the soil on Mars, the atmosphere on Jupiter and the sea on Titan.

MSACL 2015 EU, Salzburg, Austria
September 8-11, 2015
Identifying unknown unknowns with high resolution accurate mass MS in toxicology

11th International Conference of the Metabolomics Society, San Francisco, USA
June 29-July 2, 2015
Metabolomics meets quantum chemistry: a novel strategy towards reliable computer-assisted structure elucidation of metabolites

4th Conference of Czech Society for Mass Spectrometry, Hradec Kralove, CZ
April 15-17, 2015
Can quantum chemistry save the mass spectrometry?

CECE 2014, 11th International Interdisciplinary Meeting on Bioanalysis, Brno, CZ
October 20-22, 2014
A light at the end of the tunnel for the comprehensive compound identification in untargeted metabolomics

9th Aegean Analytical Chemistry Days, Chios, Greece
September 29 - October 3, 2014
Solving the Identification Bottleneck Using mzCloud, A Novel Database of High Resolution Mass Spectra

Non-Target Screening, Dübendorf, Switzerland
September 16-17, 2014
Advanced spectral processing and management

International Mass Spectrometry Conference, 2014, Geneva, Switzerland
August 24-29, 2014
Beyond the elemental composition: Computer-assisted identification methods in a high resolution era

CoSMoS 2014, Conference on Small Molecule Science, Williamsburg VA, USA
August 11-13 2014
The mzCloud - Applications of Cloud Computing in Mass Spectrometry

53rd annual meeting of the Phytochemical Society of North America, Raleigh NC, USA
August 10, 2014
A Novel Cloud Approach to Solving the Identification Bottleneck in the Untargeted Metabolomics

10th Annual International Conference of the Metabolomics Society, Tsuruoka, Japan
June, 23-26, 2014
An advanced computational and database framework for the compound identification in untargeted metabolomics

8e Journées Scientifiques du Réseau Français de Métabolomique et Fluxomique, Lyon, France
May 19-21, 2014
mzCloud and Mass Frontier: A key conceptual shift to understand “who’s who” in untargeted metabolomics

61st ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, MN, USA
June 13, 2013
Untargeted metabolomics: From statistical objects to the efficient identification of “known unknowns”

29th Montreux Symposium on LC/MS, Montreux, Switzerland
November 7, 2012
Identification of Unknowns using Mass Spectral Library Cloud

A Perspective on the Processing and Analysis of Mass Spectrometry Data, Manchester, UK
May 2, 2012
Utilizing molecular evolutionary patterns for mass spectra interpretation

Metabolomics Seminar, Stanford University, Stanford, USA
October 7, 2011
Utilizing Molecular Evolutionary Patterns for Mass Spectra Interpretation

Metabolomics Seminar, Lawrence Berkeley National Laboratory, Berkley, USA
October 6, 2011
Utilizing Molecular Evolutionary Patterns for Mass Spectra Interpretation

27th Asilomar Conference on Mass Spectrometry, San Jose, USA
October 1, 2011
Substructure Paths for Compound Identification

59th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, USA
June 9, 2011
A Third Generation Spectra Correlation Algorithm and Its Implementation in Library Search, Identification of Unknowns and Metabolite ID

TransCon 2010- Environmental Transformation of Organic Compounds, Ascona, Switzerland
September 13, 2010
Metabolite Detection and Identification

TOXCON 2010, Stará Lesná, Slovakia
September 9, 2010
Xenobiotic Metabolite Detection using High Resolution Tandem Mass Spectrometry

58th ASMS Conference on Mass Spectrometry and Allied Topics, Salt Lake City, UT, USA
May 27, 2010
Metabolite Detection and Identification Using Fragment Ion Search in Conjunction with Automated Fragment Prediction

MetaCancer Plenary Meeting, Cambridge, UK
October 2, 2009
Structure Elucidation of Small Molecules in Biomarker Research Using Mass Spectrometry
Robert Mistrik, HighChem, Slovakia

Oral Presentation - Conference on Small Molecule Science – COSMOS, Boston, MA, USA
August 4, 2009
Structural Analysis of Small Molecules Using Precursor Ion Fingerprintign (PIF)
Robert Mistrik, HighChem, Slovakia

MetaCancer Plenary Meeting, Davis, CA, USA
May 27, 2009
Identification of Novel Disease Biomarkers by Mass Spectrometry

Metabolomics Society 4th Annual Conference, Boston, MA, USA
September 3-6, 2008
A cool outlook on uncool fragmentation processes’

Metabolomics Society 4th Annual Conference, Boston, MA, USA
September 3-6, 2008
Integrated Approach for Structural Analysis of Endogenous Metabolites
Robert Mistrik, HighChem, Slovakia

1st METAcancer Meeting, Berlin, Germany
May 19-20, 2008
Strategy for identification of new breast cancer biomarkers using LC-MS and Precursor Ion fingerprinting (PIF)

Computer Application Workshop at 55th ASMS Conference, Indianapolis, IN, USA
June 3 - 7, 2007
Efficient processing of spectral, structural and chromatographic data acquired by MSn and high resolution techniques Robert Mistrik , HighChem, Slovakia

MassSpec-Forum, Vienna, Austria
February 20 - 21, 2007
A „Cool“ Outlook on „Uncool“ Fragmentation Processes

CECE 2006, Brno, Czech Republic
November 13 -14, 2006
Mass spectrometric strategy for structural mapping of endogenous metabolites

CDC Level 1 Meeting, Minnesota, MI, USA
September 26 - 28 2006
Determination of Molecular Structures by Precursor Ion Fingerprinting

54th ASMS Conference, Seattle, WA, USA
May 28 - June 1, 2006
Integrated Approach for Structural Profiling of Endogenous Metabolites
Robert Mistrik, Juraj Lutisan and Milos Suchy, HighChem, Slovakia

17th Massenspektrometrische Diskussionsveranstaltung, Vienna, Austria
February 14 - 15, 2006
Automated Determination of Molecular Structures by Precursor Ion Fingerprinting (PIF)

21st LC/MS Montreux Symposium, Switzerland
November 10-12, 2004
Harnessing the Complexity of LC-MSn Data

20th Asilomar Conference on Mass Spectrometry, Pacific Grove, CA
October 15 – 18, 2004
Mapping Human Metabolome: Is this a software problem?
Robert Mistrik, HighChem, Slovakia

9th Annual Meeting of European Network of the Official Medicines Control Laboratories (OMCLs), Langen, Germany
May 14, 2004
An ESI-MSn Library for Ion Traps: Comparable to Wiley/NIST/Maurer-Pfleger Library?

XV. Massenspektrometrischen Diskussionsveranstaltung, Vienna, Austria
February 18, 2004
A new MSn-based concept with software implementation

XIV. Massenspektrometrischen Diskussionsveranstaltung, Vienna, Austria
February 19, 2003
Data Mining in der Massenspektrometrie: Target Analyse in LC/MS/MS-Datensätzen unter Verwendung von MS/MS-Datensätzen und SOM

Vybrané publikácie

Nature Biotechnology
SPLASH, a hashed identifier for mass spectra
Gert Wohlgemuth1, Sajjan S Mehta1, Ramon F Mejia2, Steffen Neumann3, Diego Pedrosa1, Tomáš Pluskal4, Emma L Schymanski5, Egon L Willighagen6, Michael Wilson7, David S Wishart7, Masanori Arita2,8, Pieter C Dorrestein9,10, Nuno Bandeira9,11,12, Mingxun Wang11,12, Tobias Schulze13, Reza M Salek14, Christoph Steinbeck14, Venkata Chandrasekhar Nainala15, Robert Mistrik15, Takaaki Nishioka16 and Oliver Fiehn1,17 1West Coast Metabolomics Center and Genome Center University of California Davis, Davis, California, USA. 2RIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan. 3Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Halle, Germany. 4Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts, USA. 5Eawag: Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland. 6Department of Bioinformatics-BiGCaT, Maastricht University, Maastricht, The Netherlands. 7Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada. 8National Institute of Genetics, Mishima, Shizuoka, Japan. 9Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, California, USA. 10Departments of Pharmacology and Pediatrics, School of Medicine, UC San Diego, La Jolla, California, USA. 11Computer Science and Engineering, UC San Diego, La Jolla, California, USA. 12Center for Computational Mass Spectrometry, UC San Diego, La Jolla, California, USA. 13Department of Effect-Directed Analysis, UFZ Helmholtz Centre for Environmental Research GmbH, Leipzig, Germany. 14European Molecular Biology Laboratory - European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, UK. 15HighChem Ltd., Bratislava, Slovakia. 16Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Kyoto, Japan.

International Journal of Molecular Sciences
Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics
Manoj Ghaste1, Robert Mistrik2 and Vladimir Shulaev1
1Department of Biological Sciences, College of Arts and Sciences, University of North Texas, Denton, TX 76203, USA; 2HighChem, Bratislava 81104, Slovakia

Metabolites, 2016, 6(1), 8; doi:10.3390/metabo6010008
The Time Is Right to Focus on Model Organism Metabolomes
Arthur S. Edison1, Robert D. Hall2, Christophe Junot3, Peter D. Karp4, Irwin J. Kurland5, Robert Mistrik6, Laura K. Reed7, Kazuki Saito8, Reza M. Salek9, Christoph Steinbeck9, Lloyd W. Sumner10 and Mark R. Viant11,* 1Departments of Genetics and Biochemistry, Complex Carbohydrate Research Center and Institute of Bioinformatics, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA; 2Wageningen University & Research Centre, PO Box 16, 6700AA Wageningen, The Netherlands; 3CEA, iBiTec-S, Service de Pharmacologie et d’Immunoanalyse, Laboratoire d’Etude du Métabolisme des Médicaments, MetaboHUB-Paris, CEA Saclay, Building 136, 91191 Gif-sur-Yvette cedex, France; 4Bioinformatics Research Group, SRI International, 333 Ravenswood Avenue AE206, Menlo Park, CA 94025, USA; 5Albert Einstein College of Medicine, 1301 Morris Park Avenue, Bronx, NY 10461, USA; 6HighChem LLC, Leskova 11, 81105 Bratislava, Slovakia; 7Department of Biological Sciences, University of Alabama, 300 Hackberry Lane, Tuscaloosa, AL 35487, USA;8RIKEN Center for Sustainable Resource Science, Yokohama 230-0045; Chiba University, Chiba 260-8675, Japan; 9European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK; 10University of Missouri, Department of Biochemistry, Columbia, MO 65211, USA; 11School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK

Metabolomics, Volume 10, Issue 3, pp 350-353, June 2014
Metabolite identification: are you sure? And how do your peers gauge your confidence?
Darren J. Creek, Warwick B. Dunn, Oliver Fiehn, Julian L. Griffin, Robert D. Hall, Zhentian Lei, Robert Mistrik, Steffen Neumann, Emma L. Schymanski, Lloyd W. Sumner, Robert Trengove, Jean-Luc Wolfender

Journal of the American Society for Mass Spectrometry, March 2009
Determination of Ion Structures in Structurally Related Compounds Using Precursor Ion Fingerprinting
Michelle T. Sheldon1, Robert Mistrik2 and Timothy R. Croley1
1Commonwealth of Virginia, Department of General Services, Division of Consolidated Laboratory Services, 600 N 5th Street, Richmond VA 23219, United States 2HighChem, Ltd., Cajakova 18, 81105 Bratislava, Slovakia

Patent - United States Patent, No.: US 7,197,402 B2
March 27, 2007
Determination of Molecular Structures Using Tandem Mass Spectrometry
Robert Mistrik, HighChem, Slovakia

Publication - Journal of Mass Spectrometry, 2006; 41: 421-447
Comparison of CID spectra of singly charged polypeptide antibiotic precursor ions by positive-ion vacuum MALDI IT/RTOF and TOF/RTOF, AP-MALDI-IT and ESI-ITmass spectrometry Ernst Pittenauer1, Martin Zehl1, Omar Belgacem2, Emmanuel Raptakis2, Robert Mistrik3 and Gunter Allmaier1 1Institute of Chemical Technologies and Analytics, Vienna University of Technology, Vienna, Austria; 2Shimadzu Biotech Kratos Analytical, Manchester, UK; 3HighChem, Bratislava, Slovakia

Publication – Naturwissenschaften, 2004 May;91(5):209-14. Epub 2004 Mar 19
A butterfly's chemical key to various ant forts: intersection-odour or aggregate-odour multi-host mimicry?
Birgit C. Schlick-Steiner; Florian M. Steiner; Helmut Höttinger; Alexej Nikiforov; Robert Mistrik; Christa Schafellner; Peter Baier and Erhard Christian

Publication - Journal of Mass Spectrometry, 2003; 38: 924–930
Electron ionization mass spectrometric study of monomeric models of O-polysaccharides of Vibrio cholerae O:1, serotypes Ogawa and Inaba
Vladimir Kovacik; Vladimir Patoprsty; Pentti Oksman; Robert Mistrik and Pavol Kovac

Publication - Journal of Chemical Ecology, 28 (12): 2569-2584, December 2002
Cuticular Hydrocarbons of Tetramorium Ants from Central Europe: Analysis of GC-MS Data with Self-Organizing Maps (SOM) and Implications for Systematics
Florian M. Steiner ; Birgit C. Schlick-Steiner; Alexej Nikiforov; Roland Kalb and Robert Mistrik